CXCL2 anticorps (C-Term)

N° du produit ABIN401516

Détail du produit anti-CXCL2 anticorps

Antigène: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCL2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: c-KKIIEKMLKN GKSN

Specificité: This antibody detects CXCL2 / MIP-2 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptid

Immunogène: Peptide from the C-Terminus of the protein sequence according to NP_002080.1. Genename: CXCL2

Information d'application

Indications d'application: Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.2-0.6 μg/mL. Approx 17Da band observed in Human Duodenum lysates(calculated MW of 11.4 kDa according to NP_002080.1).

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur CXCL2

Antigène: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Autre désignation: CXCL2 / MIP2A (CXCL2 Produits)

Synonymes: anticorps CINC-2a, anticorps GRO2, anticorps GROb, anticorps MGSA-b, anticorps MIP-2a, anticorps MIP2, anticorps MIP2A, anticorps SCYB2, anticorps GRO3, anticorps Gro2, anticorps MIP-2, anticorps Mgsa-b, anticorps Mip2, anticorps Scyb, anticorps Scyb2, anticorps Mip-2, anticorps GROB, anticorps MIP-2alpha, anticorps C-X-C motif chemokine ligand 2, anticorps chemokine (C-X-C motif) ligand 2, anticorps CXCL2, anticorps Cxcl2

Sujet: The GRO gene was originally identified by subtractive hybridization studies between normal and tumorigenic Chinese hamster embryo fibroblasts. The hamster cDNA was cloned and used as a probe for cloning of the human GRO cDNA. The GROalpha gene initially cloned from T24 cells and the gene in melanoma cells encoding melanoma growth stimulating protein (MGSA) are identical. Human cells contain three closely related, but distinct GRO genes: GRO alpha, GRO beta, and GRO gamma. GRO beta and GRO gamma share 93 % and 82 % identity, respectively, with GRO alpha at the nucleotide level. GROs are members of the chemokine alpha family that is characterized by the separation with one amino acid of the first two cysteine residues, C-X-C, in the amino acid sequence. The GRO gene has been mapped to chromosome 4q21. In normal cells, human mRNA GRO expression is found in foreskin fibroblasts, synovial fibroblasts, chondrocytes and osteocytes. Additionally, GRO mRNA has been detected in mammary fibroblasts, mammary epithelial cells, endothelial cells, activated monocytes, macrophages, and neutrophils. Characterization of the GROalpha receptor indicates the presence of low and high affinity receptors on human neutrophils.Synonyms: C-X-C motif chemokine 2, GRO2, GROB, Gro-beta, Growth-regulated protein beta, MIP-2A, MIP2-alpha, Macrophage inflammatory protein 2-alpha, SCYB2

ID gène: 2920

NCBI Accession: NP_002080

UniProt: P19875

Pathways: Cellular Response to Molecule of Bacterial Origin