F11R anticorps (C-Term)

N° du produit ABIN401517

Détail du produit anti-F11R anticorps

Antigène: F11R (F11 Receptor (F11R))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp F11R est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: c-QPSARSEGEF KQTS

Specificité: This antibody detects CD321/JAM1 (C-term).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Pig.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide from the C-Terminus of the protein sequence according to NP_058642.1. Genename: F11R

Information d'application

Indications d'application: Peptide ELISA: Detection Limit Dilution: 1/2000. Western blot: 0.3-2 μg/mL. Approx 38 kDa band observed in Human Peripheral BloodMononucleocyte lysates (calculated MW of 32.8 kDa according to NP_058642.1). Theobserved molecular weight corresponds to earlier findings with different antibodies fromother commercial sources.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur F11R

Antigène: F11R (F11 Receptor (F11R))

Autre désignation: CD321 / JAM1 (F11R Produits)

Synonymes: anticorps CD321, anticorps JAM, anticorps JAM1, anticorps JAMA, anticorps JCAM, anticorps KAT, anticorps PAM-1, anticorps 9130004G24, anticorps AA638916, anticorps ESTM33, anticorps JAM-1, anticorps JAM-A, anticorps Jcam, anticorps Jcam1, anticorps Ly106, anticorps Jam1, anticorps F11 receptor, anticorps F11R, anticorps F11r

Sujet: Junctional Adhesion Molecule 1 (JAM1) seems to plays a role in epithelial tight junction formation. It appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. JAM1 plays a role in regulating monocyte transmigration involved in integrity of the epithelial barrier. JAM1 is also involved in platelet activation.Synonyms: F11R, JAM-A, JCAM, Junctional adhesion molecule 1, Junctional adhesion molecule A, PAM1, Platelet F11 receptor, Platelet adhesion molecule 1

ID gène: 50848

NCBI Accession: NP_058642

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization