CLIP1 anticorps (C-Term)

N° du produit ABIN401523

Détail du produit anti-CLIP1 anticorps

Antigène: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CLIP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: c-PHSTHHGSRG EERP

Specificité: This antibody detects CLIP1 / Restin at C-term. It is expected to recognize both reported isoforms (NP_002947.1, NP_937883.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Dog, PigSpecies reactivity (tested):Human.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the C-Terminus of the protein sequence according to NP_002947.1, NP_937883.1 . Genename: CLIP1

Information d'application

Indications d'application: Peptide ELISA: 1/8000. Western blot: Approx 160 kDa band observed in Human Breast Cancer lysates (calculatedMW of 160 kDa according to NP_002947.1. Recommended concentration: 1 - 3 μg/mL. Immunohistochemistry on paraffin sections: Human Thyroid Gland shows structuredcytoplasm staining in active epithelial cells. Recommended concentration: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur CLIP1

Antigène: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Autre désignation: CLIP1 / Restin (CLIP1 Produits)

Synonymes: anticorps RSN, anticorps CLIP1, anticorps clip170, anticorps clip-170, anticorps CLIP, anticorps CLIP-170, anticorps CLIP170, anticorps CYLN1, anticorps 1110007I12Rik, anticorps 4631429H07Rik, anticorps AV017631, anticorps C81039, anticorps Clip50, anticorps Rsn, anticorps mKIAA4046, anticorps restin, anticorps CAP-Gly domain containing linker protein 1, anticorps CAP-Gly domain-containing linker protein 1, anticorps CAP-Gly domain containing linker protein 1 L homeolog, anticorps CAP-GLY domain containing linker protein 1b, anticorps CAP-GLY domain containing linker protein 1, anticorps CLIP1, anticorps LOC100075022, anticorps clip1, anticorps clip1.L, anticorps clip1b, anticorps Clip1

Sujet: CLIP170 associates with the growing ends of microtubules, a type of behaviour known as 'plus end tracking' that is exhibited by proteins called +TIPS. It is known to bind to CLASPS and IQGAP1, and is thought to play a role as a positive regulator of microtubule dynamics. CLIP170 is also involved in targeting of the dynactin complex to the ends of growing microtubules, and may be important in mitosis.Synonyms: CAP-Gly domain-containing linker protein 1, CLIP-170, CYLN1, Cytoplasmic linker protein 1, Cytoplasmic linker protein 170 alpha-2, RSN, Reed-Sternberg intermediate filament-associated protein

ID gène: 6249

NCBI Accession: NP_002947

UniProt: P30622

Pathways: Dynamique des Microtubules