TREML1 anticorps (C-Term)

N° du produit ABIN401526

Détail du produit anti-TREML1 anticorps

Antigène: TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TREML1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: CGPAQNPPNN QTPS

Specificité: This antibody detects TREML1 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the C-Terminus of the protein sequence according to NP_835468.1. Genename: TREML1

Information d'application

Indications d'application: Peptide ELISA: Antibody detection limit dilution 1: 2000. Western blot: 0.3-1 μg/mL. Approx 30 kDa band observed in Human Bone Marrow lysates(calculated MW of 32.0 kDa according to NP_835468.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur TREML1

Antigène: TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))

Autre désignation: TREML1 (TREML1 Produits)

Synonymes: anticorps GLTL1825, anticorps PRO3438, anticorps TLT-1, anticorps TLT1, anticorps dJ238O23.3, anticorps 5430401J17Rik, anticorps RGD1565175, anticorps triggering receptor expressed on myeloid cells 2, anticorps triggering receptor expressed on myeloid cells like 1, anticorps triggering receptor expressed on myeloid cells-like 1, anticorps LOC474898, anticorps TREML1, anticorps Treml1

Sujet: The TREMs (triggering receptors expressed on myeloid cells) represent a family of 5 receptors clustered on murine chromosome 17. TREM-like transcript-1 (TLT-1) was initially characterized as the putative inhibitory receptor within the TREM locus on chromosome 6 and was suggested to play a critical role in modulating TREM-associated immunity. It may also play a significant role in maintaining vascular hemostasis, coagulation, and inflammation at sites of injury through its location in platelets. TREML1 is the first ITIM-containing receptor carrying a potential Src homology 3 domain ligand. TREML1 transcripts are abundant in bone marrow cells, but not in lymphocytes, and phosphorylated TREML1 associates with SHP-1, suggesting that it is indeed an inhibitory receptor.Synonyms: TLT-1, TLT1, Trem-like transcript 1 protein, Triggering receptor expressed on myeloid cells-like protein 1

ID gène: 340205

NCBI Accession: NP_835468

UniProt: Q86YW5