TNFSF14 anticorps (Internal Region)

N° du produit ABIN452686

Détail du produit anti-TNFSF14 anticorps

Antigène: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFSF14 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: c-HEVNPAAHLT GANS

Specificité: This antibody recognizes Human LIGHT. It is expected to recognize both reported isoforms (NP_003798.2, NP_742011.1). Other species not tested.

Purification: Affinity chromatography

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_003798.2, NP_742011.1.

Information d'application

Indications d'application: Peptide ELISA: 1/64000. Western blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur TNFSF14

Antigène: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Autre désignation: CD258 / LIGHT (TNFSF14 Produits)

Synonymes: anticorps TNFSF14, anticorps CD258, anticorps HVEML, anticorps LIGHT, anticorps LTg, anticorps TR2, anticorps HVEM-L, anticorps Ly113, anticorps TNF superfamily member 14, anticorps tumor necrosis factor (ligand) superfamily, member 14, anticorps TNFSF14, anticorps Tnfsf14

Sujet: LIGHT is a type II membrane protein belonging to the TNF family of membrane-anchored ligands. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells. LIGHT binds to three receptors, the herpes virus entry mediator type A receptor (HEVM), LTbR and a decoy receptor (DcR3).Synonyms: HVEM-L, HVEML, Herpesvirus entry mediator-ligand, TNFSF14, Tumor necrosis factor ligand superfamily member 14

ID gène: 8740

NCBI Accession: NP_003798

UniProt: O43557

Pathways: Cancer Immune Checkpoints