CYP2C19 anticorps (Middle Region)

N° du produit ABIN452898

Détail du produit anti-CYP2C19 anticorps

Antigène: CYP2C19 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP2C19 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects CYP2C19 at Center.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide selected from the Center region of human CYP2C19

Isotype: Ig Fraction

Information d'application

Indications d'application: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur CYP2C19

Antigène: CYP2C19 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19))

Autre désignation: CYP2C19 (CYP2C19 Produits)

Synonymes: anticorps CPCJ, anticorps CYP2C, anticorps P450C2C, anticorps P450IIC19, anticorps cytochrome P450 family 2 subfamily C member 19, anticorps cytochrome P450, family 2, subfamily C, polypeptide 19, anticorps cytochrome P450 2C19, anticorps CYP2C19

Sujet: CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within its gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.Synonyms: (R)-limonene 6-monooxygenase, CYPIIC17, CYPIIC19, Cytochrome P450 2C19, Cytochrome P450-254C, Mephenytoin 4-hydroxylase

Poids moléculaire: 55931 Da

ID gène: 1557

NCBI Accession: NP_000760

UniProt: P33261