RGS1 anticorps (N-Term)
Aperçu rapide pour RGS1 anticorps (N-Term) (ABIN453811)
Antigène
Voir toutes RGS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody reacts to RGS1.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide selected from the N-term region of human RGS1
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Indications d'application
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- RGS1 (Regulator of G-Protein Signaling 1 (RGS1))
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Autre désignation
- RGS1
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Sujet
- RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.Synonyms: 1R20, B-cell activation protein BL34, BL34, Early response protein 1R20, IER1, Regulator of G-protein signaling 1
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ID gène
- 5996
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NCBI Accession
- NP_002913
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UniProt
- Q08116
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Pathways
- Signalisation MAPK, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events
Antigène
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