KCNJ11 anticorps (AA 18-30)

N° du produit ABIN461944

Détail du produit anti-KCNJ11 anticorps

Antigène: KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))

Épitope: AA 18-30

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNJ11 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Human KCNJ11 / Kir6.2. This antibody is expected to recognise isoform 1 (NP_000516.3) only.

Homologie: Percent identity with other species by BLAST analysis: Human (100%), Gorilla (92%), Monkey (85%), Bovine (85%), Dog (85%), Bat (85%), Horse (85%), Rabbit (85%), Platypus (85%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-AEDPAKPRYRARQ from an internal region (near the N-terminus) of human KCNJ11 / Kir6.2 (NP_000516.3). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (92%), Monkey (85%), Bovine (85%), Dog (85%), Bat (85%), Horse (85%), Rabbit (85%), Platypus (85%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:32000), WB (0.1 - 0.3 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur KCNJ11

Antigène: KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))

Autre désignation: KCNJ11 / Kir6.2 (KCNJ11 Produits)

Synonymes: anticorps kir6.2, anticorps Kir6.2, anticorps mBIR, anticorps BIR, anticorps HHF2, anticorps IKATP, anticorps KIR6.2, anticorps PHHI, anticorps TNDM3, anticorps potassium voltage-gated channel subfamily J member 11, anticorps potassium inwardly-rectifying channel, subfamily J, member 11, anticorps potassium inwardly rectifying channel, subfamily J, member 11, anticorps KCNJ11, anticorps kcnj11, anticorps Kcnj11

Sujet: Name/Gene ID: KCNJ11
Subfamily: Potassium channel - inward-rectifying
Family: Ion Channel

Synonyms: KCNJ11, BIR, IKATP, HHF2, PHHI, TNDM3, Beta-cell KATP channel, KIR6.2

ID gène: 3767

NCBI Accession: NP_000516

UniProt: Q14654

Pathways: Negative Regulation of Hormone Secretion