PAK1/2 anticorps (pSer144, Ser141)

N° du produit ABIN479635

Détail du produit anti-PAK1/2 anticorps

Antigène: PAK1/2 (P21 Protein (Cdc42/Rac)-Activated Kinase 1/2 (PAK1/2))

Épitope: pSer144, Ser141

Reactivité: Humain, Rat, Souris, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK1/2 est non-conjugé

Application: Western Blotting (WB)

Specificité: Recognizes Ser144 phosphorylated PAK1 and Ser141 phosphorylated PAK2. This antibody also recognizes Ser139 phosphorylated PAK3 but does not cross-react with phosphorylated PAK4-6. The p21-activated kinase (PAK) family of serine/threonine kinases is engaged in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, control of phagocyte NADPH oxidase and growth factor-induced neurite outgrowth. Species cross-reactivity: Human and guinea pig, predicted to react with rat and mouse due to 100 % sequence homology.

Purification: Protein A purified

Immunogène: KLH-conjugated, synthetic phospho-peptide corresponding to residues surrounding Ser144 of human PAK1.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: WB (1:1000)

Usage: Suitable for use in Western Blot. Western Blot: 1:1000. Incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4?C with gentle shaking, overnight.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 100 μg/mL BSA, 50 % glycerol.

Détails sur PAK1/2

Antigène: PAK1/2 (P21 Protein (Cdc42/Rac)-Activated Kinase 1/2 (PAK1/2))

Autre désignation: PAK1/PAK2 (PAK1/2 Produits)