~38 kDa, can run at up to 45 kDa on SDS-PAGE. 1 μg/mL of this antibody was sufficient for detection of Aha1 in 10 μg of Rat tissue lysate by colorimetric Immunoblot analysis using Goat anti-Rat IgG-HRP as the secondary antibody.
Réactivité croisée (Details)
Species reactivity (tested):Human, Mouse and Rat.
Attributs du produit
Synonyms: C14orf3, HSPC322, Activator of 90 kDa heat shock protein ATPase homolog 1
ELISA. Western blot (1 μg/mL). Immunoprecipitation. Immunofluorescence. Immunocytochemistry. Immunohistochemitry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.59 mg/mL
Buffer
0.02 M Potassium Phosphate, pH 7.2 containing 0.12 M Sodium Chloride
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Date de péremption
12 months
Antigène
AHSA1
(Activator of HSP90 ATPase Activity 1 (AHSA1))
anticorps ahsa1, anticorps MGC52884, anticorps MGC132147, anticorps MGC80312, anticorps AHSA1, anticorps MGC89589, anticorps wu:fb83b05, anticorps zgc:136821, anticorps zgc:56075, anticorps AHA1, anticorps C14orf3, anticorps p38, anticorps BC023857, anticorps AHA1, activator of heat shock 90kDa protein ATPase homolog 1 S homeolog, anticorps activator of Hsp90 ATPase activity 1, anticorps AHA1, activator of heat shock 90kDa protein ATPase homolog 1 L homeolog, anticorps activator of HSP90 ATPase activity 1, anticorps AHA1, activator of heat shock 90kDa protein ATPase homolog 1, anticorps AHA1, activator of heat shock protein ATPase homolog 1a, anticorps AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast), anticorps AHA1, activator of heat shock protein ATPase 1, anticorps ahsa1.S, anticorps AHSA1, anticorps ahsa1.L, anticorps ahsa1, anticorps ahsa1a, anticorps Ahsa1
Sujet
Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).Synonyms: Activator of 90 kDa heat shock protein ATPase homolog 1, C14orf3, HSPC322