Reactivité: Hormone
WB, IHC, ELISA, IC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA: 0.31 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
8.61mg/mL (U.V. abs at 280nm)
Buffer
20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2 containing 0.09 % Sodium Azide as preservative
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Antigène
17 Hydroxyprogesterone (17 OHP)
Classe de substances
Hormone
Sujet
17-Hydroxyprogesterone (17-OH progesterone or 17OHP) is a C-21 steroid hormone produced during the synthesis of glucocorticoids and sex steroids. It is derived from progesterone via 17-hydroxylase, a P450c17 enzyme, or from 17-hydroxypregnenolone via 3-beta-hydroxysteroid dehydrogenase / Delta 5-4 isomerase. 17-Hydroxyprogesterone is a natural progestogen, and in pregnancy increases in the third trimester primarily due to fetal adrenal production. This hormone is primarily produced in the adrenal glands and to some degree in the gonads, specifically the corpus luteum of the ovary. Hydroxyprogesterone has been used for recurrent miscarriage and various menstrual disorders. Women who have had a spontaneous preterm delivery are at greatly increased risk for preterm delivery in subsequent pregnancies. The results of several small trials have suggested that hydroxyprogesterone may reduce the risk of preterm delivery.Synonyms: 17-Hydroxyprogesterone, 17-alpha-Hydroxy-Progesterone, 17OHP