Integrin Alpha2b anticorps
Aperçu rapide pour Integrin Alpha2b anticorps (ABIN4880137)
Antigène
Voir toutes Integrin Alpha2b (CD41) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognises integrin alpha 2b, a 110-130 kDa transmembrane protein that is also known as CD41. CD41 associates with the integrin CD61 to form the CD41/CD61 (GPIIb/IIIa) heterodimer, a fibronectin receptor expressed in platelets. The antibody M148 binds to some medulloblastoma and neuroblastoma cells and rhabdomyosarcoma and certain other solid tumours. No binding is observed to marrow constituents other than platelets and megakaryocytes. The antibody M148 prevents aggregation of platelets.
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Purification
- Purified on protein A from tissue culture supernatant.
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Immunogène
- Homogenized human medulloblastoma tissue.
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Isotype
- IgG1
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Indications d'application
- Optimal antibody dilution should be determined by titration
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Commentaires
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Myeloma, fusion partners: Cells from immunized Balb/c mice were fused with the P3X63Ag8.653 myeloma cell line
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Purified IgG supplied in Phosphate buffered saline (PBS) containing 0.09 % Sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Integrin Alpha2b (CD41)
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Autre désignation
- CD41
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ID gène
- 3689
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OMIM
- 607759
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UniProt
- P20701
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Pathways
- Integrin Complex
Antigène
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