MAP3K7 anticorps (C-Term)

N° du produit ABIN4886662

Détail du produit anti-MAP3K7 anticorps

Antigène: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Épitope: AA 566-603, C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K7 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase kinase kinase 7(MAP3K7) detection. Tested with WB in Human,Rat.

Séquence: RLVQEHKKLL DENKSLSTYY QQCKKQLEVI RSQQQKRQ

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase kinase kinase 7(MAP3K7) detection. Tested with WB in Human,Rat.
Gene Name: mitogen-activated protein kinase kinase kinase 7
Protein Name: Mitogen-activated protein kinase kinase kinase 7

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human TAK1 (566-603aa RLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQ), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur MAP3K7

Antigène: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Autre désignation: MAP3K7 (MAP3K7 Produits)

Synonymes: anticorps si:ch211-225h9.1, anticorps zgc:110612, anticorps Tak1, anticorps MEKK7, anticorps TAK1, anticorps TGF1a, anticorps B430101B05, anticorps C87327, anticorps mitogen-activated protein kinase kinase kinase 7, anticorps mitogen activated protein kinase kinase kinase 7, anticorps map3k7, anticorps Map3k7, anticorps MAP3K7

Sujet: Mitogen-activated protein kinase kinase kinase 7, also known as TAK1, is an enzyme that in humans is encoded by the MAP3K7 gene. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2, this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Synonyms: MAP3K 7 | MAP3K7 | MEKK7 | TAK1 | TGF1a | O43318

ID gène: 6885

UniProt: O43318

Pathways: Signalisation NF-kappaB, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway