MBD3 anticorps (C-Term)

N° du produit ABIN4916875

Détail du produit anti-MBD3 anticorps

Antigène: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Singe, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBD3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Reacts with MBD3 from human, mouse, rat, hamster, monkeys and other species (due to sequence homology)

Purification: Purified (protein A)

Immunogène: Synthetic peptide of derived from C terminal part of human MBD3.

Information d'application

Indications d'application:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M

Stock: 4 °C/-20 °C

Stockage commentaire: Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 6 months

Détails sur MBD3

Antigène: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Autre désignation: MBD3 (MBD3 Produits)

Synonymes: anticorps xmbd3, anticorps MGC69548, anticorps MBD3, anticorps DKFZp459N1635, anticorps AI181826, anticorps AU019209, anticorps methyl-CpG binding domain protein 3 S homeolog, anticorps methyl-CpG binding domain protein 3, anticorps mbd3.S, anticorps mbd3, anticorps MBD3, anticorps Mbd3

Sujet: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides. Recruits histone deacetylases and DNA methyltransferases.

ID gène: 53615

UniProt: O95983

Pathways: Chromatin Binding