SIRT2 anticorps

N° du produit ABIN5610565

Détail du produit anti-SIRT2 anticorps

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRT2 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Mouse monoclonal to SirT2.

Specificité: This antibody detects endogenous levels of SirT2 and does not cross-react with related proteins.

Attributs du produit: Mouse Monoclonal to SirT2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Purified recombinant human SirT2 protein expressed in E.coli.

Clone: 1D4-H11-H11

Isotype: IgG2b

Information d'application

Indications d'application: WB 1:500-2000
ELISA 1:10000-20000

Commentaires:

Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex. Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver. Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues. Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level). Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur SIRT2

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Autre désignation: SirT2 (SIRT2 Produits)

Synonymes: anticorps CG5085, anticorps D.mel2, anticorps Dmel\\CG5085, anticorps SIRT2, anticorps dSIRT2, anticorps sir2, anticorps Sirt2, anticorps BmSirt2, anticorps AtSRT2, anticorps SIRTUIN 2, anticorps T2K12.8, anticorps sirtuin 2, anticorps SIR2, anticorps SIR2L, anticorps SIR2L2, anticorps 5730427M03Rik, anticorps Sir2l, anticorps wu:fb57d05, anticorps zgc:55966, anticorps zgc:77003, anticorps Sirtuin 2, anticorps sirtuin 2, anticorps sirtuin 2 S homeolog, anticorps NAD-dependent deacetylase sirtuin 2 homolog, anticorps sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae), anticorps Sirt2, anticorps SIRT2, anticorps sirt2.S, anticorps SRT2, anticorps sirt2

Poids moléculaire: 43kDa

ID gène: 22933

UniProt: Q8IXJ6