AANAT anticorps

N° du produit ABIN4902802

Détail du produit anti-AANAT anticorps

Antigène: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AANAT est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: A synthetic peptide of human AANAT

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:1000

Commentaires:

Highly expressed in pineal gland and at lower levels in the retina, Weak expression in several brain regions and in the pituitary gland

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur AANAT

Antigène: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Autre désignation: AANAT (AANAT Produits)

Synonymes: anticorps DSPS, anticorps SNAT, anticorps AA-NAT, anticorps Nat4, anticorps Nat-2, anticorps Snat, anticorps aralkylamine N-acetyltransferase, anticorps arylalkylamine N-acetyltransferase, anticorps AANAT, anticorps Aanat

Sujet: The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 23.344 kDa

ID gène: 15

UniProt: Q16613

Pathways: Photoperiodism