AUH anticorps

N° du produit ABIN4902991

Détail du produit anti-AUH anticorps

Antigène: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AUH est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: The methylglutaconyl-CoA hydratase, mitochondrial protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92 % identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40- kDa precursor protein which is subsequently processed to a 32- kDa mature form.

Purification: Affinity purification

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C.

Détails sur AUH

Antigène: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Autre désignation: AUH (AUH Produits)

Synonymes: anticorps C77140, anticorps W91705, anticorps wu:fb81b10, anticorps zgc:101057, anticorps AU RNA binding methylglutaconyl-CoA hydratase, anticorps AU RNA binding protein/enoyl-coenzyme A hydratase, anticorps AU RNA binding protein/enoyl-CoA hydratase, anticorps AU RNA binding protein/enoyl-CoA hydratase S homeolog, anticorps AUH, anticorps Auh, anticorps auh, anticorps auh.S

ID gène: 549

UniProt: Q13825