CDH10 anticorps

N° du produit ABIN4903221

Détail du produit anti-CDH10 anticorps

Antigène: CDH10 (Cadherin 10, Type 2 (T2-Cadherin) (CDH10))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDH10 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. Mutations in this gene may be associated with lung squamous cell carcinoma and colorectal cancer in human patients.

Purification: Affinity purification

Immunogène: Recombinant protein of human CDH10.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C.

Détails sur CDH10

Antigène: CDH10 (Cadherin 10, Type 2 (T2-Cadherin) (CDH10))

Autre désignation: CDH10 (CDH10 Produits)

Synonymes: anticorps A830016G23Rik, anticorps C030003B10Rik, anticorps C030011H18Rik, anticorps cadherin 10, anticorps Cdh10, anticorps CDH10

ID gène: 1008

UniProt: Q9Y6N8

Pathways: Cell-Cell Junction Organization