Hemoglobin Subunit beta anticorps
HBB
Reactivité: Humain, Souris, Rat
WB, IHC, FACS
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN4903870
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Antigène
Voir toutes Hemoglobin Subunit beta (HBB) Anticorps
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Hemoglobin Subunit beta (HBB)
(Hemoglobin beta (HBB))
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Reactivité
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Humain, Souris, Rat
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Hôte
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Lapin
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Clonalité
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Polyclonal
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Conjugué
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Cet anticorp Hemoglobin Subunit beta est non-conjugé
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Application
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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
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Attributs du produit
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Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The å (16p13.3, 5'-Ω-pseudoz-pseudo å2-pseudo å1-å2-å1-1-3') and (11p15.5) globin loci determine the basic hemoglobin structure. The globin portion of hemoglobin consists of two å chains and two chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between å and chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the å1-2 cleavage plane. When the two å1-2 interfaces are closely bound, hemoglobin has a low affinity for oxygen. Hb A, which contains two å chains plus two chains, comprises 97 % of total circulating hemoglobin. The remaining 3 % of total circulating hemoglobin is comprised of Hb A-2, which consists of two å chains plus two chains, and fetal hemoglobin (Hb F), which consists of two å chains together with two © chains.
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Purification
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Affinity purification
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Immunogène
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Recombinant protein of human HBB.
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Isotype
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IgG
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Top Product
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Discover our top product HBB Anticorps primaire
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Indications d'application
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WB 1:100-1:200 , IHC 1:50-1:100 , FC 1:20-1:50
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Restrictions
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For Research Use only
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Format
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Liquid
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Concentration
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1 mg/mL
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Buffer
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PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
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Agent conservateur
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Sodium azide
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Précaution d'utilisation
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This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
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Stock
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-20 °C
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Stockage commentaire
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Store at -20°C.
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Antigène
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Hemoglobin Subunit beta (HBB)
(Hemoglobin beta (HBB))
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Autre désignation
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HBB (HBB Produits)
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Synonymes
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anticorps HBB, anticorps HBB1, anticorps HBBA, anticorps HBBB, anticorps CD113t-C, anticorps beta-globin, anticorps hbb, anticorps hemoglobin, beta, anticorps hemoglobin subunit beta, anticorps hemoglobin subunit beta-like, anticorps beta globin, anticorps hemoglobin beta chain complex, anticorps hemoglobin subunit beta-1, anticorps HBB, anticorps HBB2, anticorps LOC100720944, anticorps LOC480784, anticorps Hbb, anticorps LOC100136576, anticorps LOC101098159, anticorps LOC100976465, anticorps LOC100410611, anticorps LOC105468624
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Classe de substances
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Viral Protein
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ID gène
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3043
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UniProt
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P68871
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