CD3 epsilon anticorps

N° du produit ABIN4949512

L’anticorps anti-CD3 epsilon Monoclonal Souris est utilisé pour la détection de CD3 epsilon dans des échantillons de Humain et Singe. Il a été validé pour FACS, IF et Act.

Aperçu rapide pour CD3 epsilon anticorps (ABIN4949512)

Antigène: CD3 epsilon (CD3E)

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3 epsilon est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Activation (Act)

Clone: CRIS-7

Détail du produit anti-CD3 epsilon anticorps

Purification: Protein G affinity chromatography

Immunogène: Stimulated human leukocytes were used as the immunogen for the CD3e antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal dilution of the CD3e antibody should be determined by the researcher.\. Functional Activity: Induce T cell activation and proliferation (Order SAF formulation),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD3e antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur CD3 epsilon

Antigène: CD3 epsilon (CD3E)

Autre désignation: CD3e

Sujet: Recognizes the epsilon-chain of CD3 (Workshop V, Code: CD03.09), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28  kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway