VLDLR
Reactivité: Humain, Rat, Souris, Chien, Porc, Poulet, Boeuf (Vache)
WB, FACS
Hôte: Lapin
Polyclonal
PE-Cy5.5
Indications d'application
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the VLDL Receptor antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/10^6 cells in 0.1ml,IF: 1-2 μg/mL,Western blot: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT
Restrictions
For Research Use only
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
4 °C,-20 °C
Stockage commentaire
Store the VLDL Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Antigène
VLDLR
(Very Low Density Lipoprotein Receptor (VLDLR))
anticorps CARMQ1, anticorps CHRMQ1, anticorps VLDLRCH, anticorps AA408956, anticorps AI451093, anticorps AW047288, anticorps vldlr, anticorps very low density lipoprotein receptor, anticorps very low density lipoprotein receptor S homeolog, anticorps VLDLR, anticorps Vldlr, anticorps vldlr.S
Sujet
Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.