DLG1 anticorps (AA 1-165)
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- Antigène Voir toutes DLG1 Anticorps
- DLG1 (Discs, Large Homolog 1 (DLG1))
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Épitope
- AA 1-165
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DLG1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogène
- Amino acids 1-165 of human SAP97 were used as the immunogen for the SAP97 antibody.
- Isotype
- IgG
- Top Product
- Discover our top product DLG1 Anticorps primaire
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- Indications d'application
- Optimal dilution of the SAP97 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the SAP97 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- DLG1 (Discs, Large Homolog 1 (DLG1))
- Autre désignation
- SAP97 / DLG1 (DLG1 Produits)
- Synonymes
- anticorps DLG1, anticorps Dlgh1, anticorps SAP97, anticorps B130052P05Rik, anticorps E-dlg/SAP97, anticorps SAP-97, anticorps mKIAA4187, anticorps DLGH1, anticorps dJ1061C18.1.1, anticorps hdlg, anticorps discs large MAGUK scaffold protein 1, anticorps discs, large homolog 1 (Drosophila), anticorps DLG1, anticorps Dlg1
- Sujet
- Disks large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a protein that in humans is encoded by the SAP97 gene. SAP97 is expressed throughout the body in epithelial cells, including the kidney and brain. There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, and may interact with HPV. In the brain, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane. SAP97's function has been investigated by reducing its expression by knockout or increasing its expression heterologously. Mice in which the SAP97 gene has been knocked out die perinatally, have a cleft palate, and deficiencies in renal function. Overexpression of SAP97 in mammalian neurons leads to increased synaptic strength.
- UniProt
- Q12959
- Pathways
- Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response
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