PRKAB2 anticorps (AA 3-33)

N° du produit ABIN3032387

Détail du produit anti-PRKAB2 anticorps

Antigène: PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))

Épitope: AA 3-33

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAB2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 3-33 from human PRKAB2 was used as the immunogen for this AMPK beta 2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the AMPK beta 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the AMPK beta 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur PRKAB2

Antigène: PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))

Autre désignation: AMPK beta 2 (PRKAB2) (PRKAB2 Produits)

Synonymes: anticorps prkab2, anticorps MGC64365, anticorps PRKAB2, anticorps DKFZp469M1118, anticorps 5730553K21Rik, anticorps AW049591, anticorps BB124140, anticorps protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog, anticorps protein kinase AMP-activated non-catalytic subunit beta 2, anticorps protein kinase, AMP-activated, beta 2 non-catalytic subunit, anticorps prkab2.L, anticorps PRKAB2, anticorps prkab2, anticorps Prkab2

Sujet: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

UniProt: O43741

Pathways: AMPK Signaling, L'effet Warburg