EGF anticorps (AA 940-967)
Aperçu rapide pour EGF anticorps (AA 940-967) (ABIN3030833)
Antigène
Voir toutes EGF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 940-967
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 940-967 from the human protein was used as the immunogen for this anti-EGF antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the anti-EGF antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the anti-EGF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- EGF (Epidermal Growth Factor (EGF))
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Autre désignation
- EGF
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Sujet
- This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
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UniProt
- P01133
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Pathways
- Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
Antigène
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