EGFR anticorps (AA 1004-1033)

N° du produit ABIN3030837

Cet anticorps anti-EGFR Polyclonal Lapin (ABIN3030837) détecte spécifiquement EGFR dans WB, IHC, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour EGFR anticorps (AA 1004-1033) (ABIN3030837)

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGFR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Détail du produit anti-EGFR anticorps

Épitope: AA 1004-1033

Fonction: Anti-EGFR Antibody

Purification: Antigen affinity

Immunogène: A portion of amino acids 1004-1033 from the human protein was used as the immunogen for this anti-EGFR antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the anti-EGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the anti-EGFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur EGFR

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Autre désignation: EGFR

Sujet: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

UniProt: P00533

Pathways: Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins