anticorps ARO, anticorps ARO1, anticorps CPV1, anticorps CYAR, anticorps CYP19, anticorps CYPXIX, anticorps P-450AROM, anticorps Aromatase, anticorps Cyp19, anticorps Cyp19a, anticorps p450arom, anticorps P450 arom, anticorps aro, anticorps cyp19, anticorps cyp19a, anticorps p450arom-A, anticorps P450AROM, anticorps Ar, anticorps ArKO, anticorps Int-5, anticorps Int5, anticorps CYP19P1, anticorps CYP19A1, anticorps CYP19a1, anticorps P450aromA, anticorps ar1, anticorps cypXIX, anticorps etID309862.18, anticorps zgc:136541, anticorps AroB, anticorps CYP19a2, anticorps P450aromB, anticorps cyp19b, anticorps zgc:92614, anticorps cyp19a1, anticorps cytochrome P450 family 19 subfamily A member 1, anticorps cytochrome P450, family 19, subfamily a, polypeptide 1, anticorps cytochrome P450 family 19 subfamily A member 1 L homeolog, anticorps aromatase, anticorps cytochrome P450 aromatase, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1, anticorps cytochrome P450 19A1, anticorps cytochrome P450, family 17, subfamily A, polypeptide 1, anticorps cytochrome P450, family 19, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1a, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1b, anticorps cytochrome P450 19A1-like, anticorps CYP19A1, anticorps Cyp19a1, anticorps cyp19a1.L, anticorps SAV_2383, anticorps pfcyp19b-tstr, anticorps CYP19, anticorps cyp19a1a, anticorps cyp19a1b, anticorps LOC101174651
Sujet
CYP19A1/Aromatase is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity, the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.