BRAF anticorps (AA 580-609)
Aperçu rapide pour BRAF anticorps (AA 580-609) (ABIN3029543)
Antigène
Voir toutes BRAF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 580-609
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Réactivité croisée (Details)
- Expected species reactivity: Chicken, Mouse
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 580-609 from the human protein was used as the immunogen for this BRAF antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the BRAF antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,IHC (Paraffin): 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the BRAF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
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Autre désignation
- BRAF
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Sujet
- BRAF, a member of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.
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UniProt
- P15056
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Pathways
- Signalisation MAPK, Signalisation RTK, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
Antigène
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