CD3 epsilon anticorps (AA 154-182)

N° du produit ABIN3030389

L’anticorps Lapin Polyclonal anti-CD3 epsilon a été validé pour WB et ELISA. Il convient pour détecter CD3 epsilon dans des échantillons de Humain.

Aperçu rapide pour CD3 epsilon anticorps (AA 154-182) (ABIN3030389)

Antigène: CD3 epsilon (CD3E)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD3 epsilon est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CD3 epsilon anticorps

Épitope: AA 154-182

Réactivité croisée (Details): Expected species reactivity: Primate

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 154-182 from the human protein was used as the immunogen for this CD3e antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the CD3e antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CD3e antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur CD3 epsilon

Antigène: CD3 epsilon (CD3E)

Autre désignation: CD3e

Sujet: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

UniProt: P07766

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway