COL1A1
Reactivité: Humain
WB, IHC, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Titration of the COL1A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the COL1A1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
anticorps OI4, anticorps Col1a-1, anticorps Cola-1, anticorps Cola1, anticorps Mov-13, anticorps Mov13, anticorps COLIA1, anticorps col1a1, anticorps MGC52532, anticorps COL1A1, anticorps COL1A2, anticorps alpha1(I), anticorps cb21, anticorps sb:cb21, anticorps sb:cb384, anticorps wu:fa99c12, anticorps wu:fb02c06, anticorps alpha3(I), anticorps col1a3, anticorps hm:zeh0348, anticorps wu:fa95h05, anticorps wu:fd02a10, anticorps wu:fj59a10, anticorps collagen type I alpha 1 chain, anticorps collagen, type I, alpha 1, anticorps collagen, type I, alpha 1 S homeolog, anticorps collagen alpha-1(I) chain, anticorps collagen type I alpha 2 chain, anticorps collagen, type I, alpha 1a, anticorps collagen 1a1, anticorps collagen, type I, alpha 1b, anticorps COL1A1, anticorps Col1a1, anticorps col1a1.S, anticorps LOC397571, anticorps COL1A2, anticorps col1a1a, anticorps col1a1, anticorps col1a1b
Sujet
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish].