TNFRSF21 anticorps (AA 356-385)

N° du produit ABIN3029370

Détail du produit anti-TNFRSF21 anticorps

Antigène: TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))

Épitope: AA 356-385

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF21 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 356-385 from the human protein was used as the immunogen for this DR6 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the DR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DR6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TNFRSF21

Antigène: TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))

Autre désignation: DR6 (Death Receptor 6) (TNFRSF21 Produits)

Synonymes: anticorps TNFRSF21, anticorps tnfrsf21, anticorps MGC146356, anticorps BM-018, anticorps CD358, anticorps DR6, anticorps AA959878, anticorps R74815, anticorps TR7, anticorps dr6, anticorps im:6795346, anticorps wu:fa55e01, anticorps wu:fb02e11, anticorps wu:fc29a09, anticorps wu:fi27h08, anticorps TNF receptor superfamily member 21, anticorps tumor necrosis factor receptor superfamily member 21, anticorps tumor necrosis factor receptor superfamily, member 21, anticorps TNFRSF21, anticorps tnfrsf21, anticorps Tnfrsf21

Sujet: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.

UniProt: O75509

Pathways: Regulation of Lipid Metabolism by PPARalpha