MCL-1 anticorps (AA 191-226)
Aperçu rapide pour MCL-1 anticorps (AA 191-226) (ABIN3031299)
Antigène
Voir toutes MCL-1 (MCL1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 191-226
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Fonction
- MCL1 Antibody
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Purification
- Purified
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Immunogène
- A portion of amino acids 191-226 from the human protein was used as the immunogen for this MCL1 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the MCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the MCL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
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Autre désignation
- MCL1
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Sujet
- The Mcl-1 protein belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
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UniProt
- Q07820
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Pathways
- Signalisation MAPK
Antigène
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