BRAF anticorps (pThr400)
Aperçu rapide pour BRAF anticorps (pThr400) (ABIN3029548)
Antigène
Voir toutes BRAF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pThr400
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Réactivité croisée (Details)
- Expected species reactivity: Mouse
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Purification
- Antigen affinity purified
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Immunogène
- This phospho-BRAF antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT400 of human BRAF.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the phospho-BRAF antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the phospho-BRAF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
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Autre désignation
- BRAF
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Sujet
- BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
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UniProt
- P15056
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Pathways
- Signalisation MAPK, Signalisation RTK, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
Antigène
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