EGFR anticorps (pSer768)
Aperçu rapide pour EGFR anticorps (pSer768) (ABIN3030842)
Antigène
Voir toutes EGFR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer768
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Fonction
- Phospho-EGF Receptor / EGFR Antibody (pS768)
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Homologie
- Mouse
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Purification
- Antigen affinity purified
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Immunogène
- This phospho-EGFR antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS768 of human EGFR.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the phospho-EGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the phospho-EGFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Autre désignation
- EGFR
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Sujet
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Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. EGFR is a receptor for EGF, but also for other members of the EGF family, including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. It is involved in the control of cell growth and differentiation.
Explore our < a href=../tds/egfr-antibody-epidermal-growth-factor-receptor-31g7-v2485>EGFR Antibody (31G7) page for a broader view of EGFR expression and extensively validated antibody performance across applications. -
UniProt
- P00533
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Pathways
- Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
Antigène
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