TIGIT anticorps (AA 12-142)

N° du produit ABIN4955607

Détail du produit anti-TIGIT anticorps

Antigène: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Épitope: AA 12-142

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIGIT est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: A portion of amino acids 12-142 from the human protein was used as the immunogen for this TIGIT antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the TIGIT antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TIGIT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TIGIT

Antigène: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Autre désignation: TIGIT (TIGIT Produits)

Synonymes: anticorps VSIG9, anticorps VSTM3, anticorps WUCAM, anticorps ENSMUSG00000071552, anticorps Vstm3, anticorps RGD1563191, anticorps T-cell immunoreceptor with Ig and ITIM domains, anticorps T cell immunoreceptor with Ig and ITIM domains, anticorps TIGIT, anticorps Tigit

Sujet: TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

UniProt: Q495A1

Pathways: Cancer Immune Checkpoints