UBA52 anticorps (C-Term)

N° du produit ABIN498041

Détail du produit anti-UBA52 anticorps

Antigène: UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBA52 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: Recognizes Ubiquitin, Ribosomal Protein L40 (UBA52).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography

Immunogène: Synthetic peptide kLH conjugated synthetic peptide selected from the C-terminal region of Human Ubiquitin .Remarks: Antigen Modification: C-Terminus

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/50-1/100Western blot: 1/100-1/500Immunohistochemistry on Paraffin Sections: 10 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur UBA52

Antigène: UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))

Autre désignation: UBA52 (UBA52 Produits)

Synonymes: anticorps CEP52, anticorps HUBCEP52, anticorps L40, anticorps RPL40, anticorps D8Ertd21e, anticorps Gm1863, anticorps Rps27a, anticorps Ubb, anticorps Ubc, anticorps UBCEP2, anticorps UB-RPL40, anticorps MGC80109, anticorps cep52, anticorps hubcep52, anticorps rpl40, anticorps RPS27A, anticorps UBB, anticorps UBC, anticorps wu:fa91f08, anticorps zgc:123344, anticorps UBA52, anticorps ubiquitin A-52 residue ribosomal protein fusion product 1, anticorps ubiquitin A-52 residue ribosomal protein fusion product 1 L homeolog, anticorps UBA52, anticorps Uba52, anticorps uba52.L, anticorps uba52

Sujet: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.Synonyms: CEP52, UBCEP2, Ubiquitin A-52 residue ribosomal protein fusion product 1, Ubiquitin-60S ribosomal protein L40

ID gène: 7311

NCBI Accession: NP_001029102

UniProt: P62987

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation