ATP1A1 anticorps

N° du produit ABIN498101

Détail du produit anti-ATP1A1 anticorps

Antigène: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP1A1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody antibody detects endogenous levels of Na(+)/K(+)-ATPase alpha1 protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: Western Blots: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/100approx. 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ATP1A1

Antigène: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Autre désignation: ATP1A1 (ATP1A1 Produits)

Synonymes: anticorps Atpa-1, anticorps BC010319, anticorps Nkaa1b, anticorps K-ATPase, anticorps Na+K+ATPase, anticorps atp1a1, anticorps atp1a1a.1, anticorps atp1a1l1, anticorps atp[a]1B1, anticorps cb70, anticorps wu:fa03c03, anticorps wu:fb92h10, anticorps atp1a1l5, anticorps atp[a]1B2, anticorps cb707, anticorps wu:fj34g01, anticorps zgc:92351, anticorps ATPase Na+/K+ transporting subunit alpha 1, anticorps ATPase, Na+/K+ transporting, alpha 1 polypeptide, anticorps ATPase Na+/K+ transporting subunit alpha 1 L homeolog, anticorps ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 1, anticorps ATPase, Na+/K+ transporting, alpha 1b polypeptide, anticorps ATP1A1, anticorps Atp1a1, anticorps atp1a1.L, anticorps atp1a1a.1, anticorps atp1a1b

Sujet: The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP dependent transport of sodium and potassium across the cell membrane. This membrane bound enzyme is related to a number of other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA). The sodium / potassium ATPase consists of a large, multipass, transmembrane catalytic subunit, termed the alpha subunit, and an associated smaller glycoprotein, termed the beta subunit. Studies indicate that there are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1 and beta 2) encoded by two multigene families.The different isoforms of the sodium / potassium ATPase exhibit tissue specific and developmental patterns of expression. The alpha 1 and beta mRNAs are present in all cell types examined, whereas the alpha 2 and alpha 3 mRNAs exhibit a more restricted pattern of cell specific expression. The alpha subunit has been found in kidney, brain, heart, and to a lesser extent liver, skeletal and smooth muscle.Synonyms: Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-1

Poids moléculaire: approx. 112 kDa

ID gène: 476

NCBI Accession: NP_000692

UniProt: P05023

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process