IL2 Receptor beta anticorps

N° du produit ABIN498147

Détail du produit anti-IL2 Receptor beta anticorps

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL2 Receptor beta est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of IL-2Rβ protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur IL2 Receptor beta

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Autre désignation: CD122 / IL2RB (IL2RB Produits)

Synonymes: anticorps IL2RB, anticorps il-2rb, anticorps CD122, anticorps IL15RB, anticorps P70-75, anticorps IL2RBC, anticorps IL-15Rbeta, anticorps IL15Rbeta, anticorps Il-2/15Rbeta, anticorps Il-2Rbeta, anticorps p70, anticorps interleukin 2 receptor subunit beta, anticorps interleukin-2 receptor subunit beta, anticorps interleukin 2 receptor, beta, anticorps interleukin 2 receptor, beta chain, anticorps IL2RB, anticorps LOC510185, anticorps il2rb, anticorps Il2rb

Sujet: The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolysis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown.Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75

Poids moléculaire: approx. 60 kDa

ID gène: 3560

NCBI Accession: NP_000869

UniProt: P14784

Pathways: Signalistation JAK/STAT, Growth Factor Binding