KIF11 anticorps

N° du produit ABIN498151

Détail du produit anti-KIF11 anticorps

Antigène: KIF11 (Kinesin Family Member 11 (KIF11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF11 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Eg5 protein.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur KIF11

Antigène: KIF11 (Kinesin Family Member 11 (KIF11))

Autre désignation: KIF11 (KIF11 Produits)

Synonymes: anticorps EG5, anticorps HKSP, anticorps KNSL1, anticorps MCLMR, anticorps TRIP5, anticorps Eg5, anticorps Kif8, anticorps Kifl1, anticorps Knsl1, anticorps F2H17.19, anticorps F2H17_19, anticorps DDBDRAFT_0189194, anticorps DDBDRAFT_0201556, anticorps DDB_0189194, anticorps DDB_0201556, anticorps XLEg5K1, anticorps XlEg5, anticorps cos2, anticorps costal2, anticorps eg5, anticorps hksp, anticorps kif11, anticorps kif11-a, anticorps kif11-b, anticorps kif11b, anticorps knsl1, anticorps trip5, anticorps Cos2, anticorps Costal2, anticorps XLEg5K2, anticorps kif11a, anticorps kinesin family member 11, anticorps P-loop containing nucleoside triphosphate hydrolases superfamily protein, anticorps kinesin family member 11 S homeolog, anticorps kinesin family member 11 L homeolog, anticorps KIF11, anticorps Kif11, anticorps AT2G36200, anticorps kif11, anticorps kif11.S, anticorps kif11.L

Sujet: Eukaryotes contain a superfamily of microtubule-based motor proteins comprising Kinesin and a number of related proteins that are thought to participate in various forms of intracellular motility, including cell division and organelle transport. Eg5 (also known as Kinesin-like protein KIF11 or TRIP5) is a slow, plus-end-directed microtubule-based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. When the expression of Eg5 is blocked, centrosome migration halts and cells are arrested in mitosis with monoastral microtubule arrays. Eg5 is phosphorylated on serine during S phase and on both serine and Thr 927 during mitosis, which regulates the association of Eg5 with the spindle apparatus (probably during early prophase). Eg5 is also known to be a member of the thyroid receptor interacting protein (TRIP) family, and interacts with the thyroid hormone receptor only in the presence of thyroid hormone.Synonyms: EG5, KIF11, KNSL1, Kinesin-like protein 1, Kinesin-like protein KIF11, Kinesin-like spindle protein HKSP, Kinesin-related motor protein Eg5, TRIP-5, TRIP5, Thyroid receptor-interacting protein 5

Poids moléculaire: approx. 119 kDa

ID gène: 3832

NCBI Accession: NP_004514

UniProt: P52732