IL16 anticorps

N° du produit ABIN498681

Détail du produit anti-IL16 anticorps

Antigène: IL16 (Interleukin 16 (IL16))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL16 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of IL-16 protein. (region surrounding Gly97)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL16

Antigène: IL16 (Interleukin 16 (IL16))

Autre désignation: Interleukin-16 / IL16 (IL16 Produits)

Synonymes: anticorps IL16, anticorps LCF, anticorps NIL16, anticorps PRIL16, anticorps prIL-16, anticorps mKIAA4048, anticorps IL-16, anticorps interleukin 16, anticorps IL16, anticorps Il16

Sujet: Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, intiate signal transduction cascades that elicit physiological changes in their target cells. Interleukin-16, or IL-16, is a cytokine that has chemoattractant activity on CD4+ T lymphocytes. It has long been known that eosinophils and CD4+ T lymphocytes are recruited to sites of allergic inflammation, but the molecular mechanism was poorly understood. IL-16, also referred to as lymphocyte chemoattractant factor, is secreted by activated eosinophils as part of the allergic response along with RANTES, an additional cytokine. Once bound to its cognate receptor, CD4, IL-16 initiates a signal cascade that results in the activation of the PKC family.Synonyms: IL-16, LCF, Lymphocyte chemoattractant factor

ID gène: 3603

NCBI Accession: NP_004504

UniProt: Q14005