CAMK2A
Reactivité: Humain
ELISA, IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
anticorps camk2, anticorps camk2b, anticorps zgc:112538, anticorps zgc:123320, anticorps CAMKA, anticorps CaMKII, anticorps R74975, anticorps mKIAA0968, anticorps PK2CDD, anticorps PKCCD, anticorps calcium/calmodulin dependent protein kinase II alpha, anticorps calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog, anticorps calcium/calmodulin-dependent protein kinase II alpha, anticorps CAMK2A, anticorps camk2a.S, anticorps camk2a, anticorps Camk2a
Sujet
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated α, β, γ and δ, which may or may not be co-expressed in the same tissue type. CaMKIIα is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.Synonyms: CAMKA, CaM kinase II subunit alpha, CaM-kinase II alpha chain, CaMK-II subunit alpha, Calcium/calmodulin-dependent protein kinase type II alpha chain, KIAA0968