IQCB1 anticorps

N° du produit ABIN498968

Détail du produit anti-IQCB1 anticorps

Antigène: IQCB1 (IQ Motif Containing B1 (IQCB1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IQCB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Nephrocystin-5 protein. (region surrounding Arg467)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IQCB1

Antigène: IQCB1 (IQ Motif Containing B1 (IQCB1))

Autre désignation: IQCB1 (IQCB1 Produits)

Synonymes: anticorps piq, anticorps nphp5, anticorps slsn5, anticorps MGC81507, anticorps IQCB1, anticorps zgc:101792, anticorps MGC146213, anticorps 6820449I09Rik, anticorps AV128382, anticorps NPHP5, anticorps PIQ, anticorps SLSN5, anticorps IQ motif containing B1, anticorps IQ motif containing B1 L homeolog, anticorps IQ calmodulin-binding motif containing 1, anticorps Iqcb1, anticorps iqcb1.L, anticorps IQCB1, anticorps iqcb1

Sujet: CEP290 activates ATF4 mediated transcription and is required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells, may play a role in ciliary transport processes. CEP290 is ubiquitously expressed, strongly in placenta and weakly in brain. There are two named isoforms. Defects in CEP290 are a cause of Joubert syndrome type 5 (JBTS5) [MIM:610188], Senior-Loken syndrome type 6 (SLSN6) [MIM:610189], Leber congenital amaurosis type 10 (LCA10) [MIM:611755] and Meckel syndrome type 4 (MKS4) [MIM:611134]. Antibodies against CEP290 are present in sera from patients with cutaneous T cell lymphomas, but not in the healthy control population.Synonyms: IQ calmodulin-binding motif-containing protein 1, KIAA0036, NPHP5, OK/SW-cl.85

Poids moléculaire: approx. 69 kDa

ID gène: 9657

NCBI Accession: NP_001018864

UniProt: Q15051