CDC42EP2 anticorps

N° du produit ABIN499043

Détail du produit anti-CDC42EP2 anticorps

Antigène: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC42EP2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of Cdc42EP2 protein. (region surrounding Leu24)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CDC42EP2

Antigène: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Autre désignation: CDC42EP2 (CDC42EP2 Produits)

Synonymes: anticorps CDC42EP2, anticorps zgc:103557, anticorps BORG1, anticorps CEP2, anticorps 1110008C05Rik, anticorps Borg1, anticorps Cep2, anticorps D19Bwg1013e, anticorps CDC42 effector protein 2, anticorps CDC42 effector protein 2 S homeolog, anticorps CDC42 effector protein (Rho GTPase binding) 2, anticorps CDC42EP2, anticorps cdc42ep2.S, anticorps cdc42ep2, anticorps Cdc42ep2

Sujet: Cdc42, a small GTPase, regulates Actin polymerization, elongation of cell shape and cell signaling through interactions with many different downstream effector proteins, most of which contain a Cdc42-binding motif known as a CRIB domain. Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the Actin cytoskeleton and may also influence Actin filament assembly and overall cell shape.Synonyms: BORG1, Binder of Rho GTPases 1, CEP2, Cdc42 effector protein 2

Poids moléculaire: approx. 30 kDa

ID gène: 10435

NCBI Accession: NP_006770

UniProt: O14613

Pathways: Regulation of Actin Filament Polymerization