DPYSL4 anticorps

N° du produit ABIN499060

Détail du produit anti-DPYSL4 anticorps

Antigène: DPYSL4 (Dihydropyrimidinase-Like 4 (DPYSL4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPYSL4 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of CRMP-3 protein. (region surrounding Cys132)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DPYSL4

Antigène: DPYSL4 (Dihydropyrimidinase-Like 4 (DPYSL4))

Autre désignation: DPYSL4 / CRMP3 (DPYSL4 Produits)

Synonymes: anticorps CRMP3A, anticorps CRMP3B, anticorps crmp3, anticorps crmp3-a, anticorps MGC53768, anticorps DPYSL4, anticorps drp-4, anticorps ulip4, anticorps CRMP-3, anticorps CRMP3, anticorps DRP-4, anticorps ULIP4, anticorps AI173505, anticorps Crmp3, anticorps DPY4, anticorps Drp-4, anticorps Ulip4, anticorps Dpys4, anticorps dihydropyrimidinase like 4, anticorps dihydropyrimidinase like 4 L homeolog, anticorps dihydropyrimidinase-like 4, anticorps DPYSL4, anticorps dpysl4.L, anticorps dpysl4, anticorps Dpysl4

Sujet: Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to Semaphorin 3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum. It is cleaved by Calpain to produce a p54 N-terminal fragment. This cleavage product translocates to the nucleus and induces neuronal death in response to excitotoxicity and cerebral ischemia.Synonyms: Collapsin response mediator protein 3, DRP-4, Dihydropyrimidinase-related protein 4, ULIP4, UNC33-like phosphoprotein 4

Poids moléculaire: approx. 50 kDa

ID gène: 10570

NCBI Accession: NP_006417

UniProt: O14531