ARHGDIB anticorps (N-Term)

N° du produit ABIN499142

Détail du produit anti-ARHGDIB anticorps

Antigène: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Épitope: N-Term

Reactivité: Humain, Boeuf (Vache), Chien, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGDIB est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: TEKAPEPHVE -C

Specificité: Recognizes ARHGDIB.

Réactivité croisée (Details): Species reactivity (expected):Canine, Pig, Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the N Terminus of the protein sequence according to NP_001166.3. Genename: ARHGDIB

Information d'application

Indications d'application: Peptide ELISA: Limit Dilution: 1/4000. Western blot: 1-3 μg/mL. This antibody detects a band of approx. 26 kDa in lysates of cell lineJurkat.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ARHGDIB

Antigène: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Autre désignation: ARHGDIB / D4-GDI (ARHGDIB Produits)

Synonymes: anticorps ARHGDIB, anticorps zgc:65966, anticorps arhgdib, anticorps MGC69067, anticorps gdia2, anticorps rhodgi-2, anticorps rhodgi2, anticorps D4, anticorps GDIA2, anticorps GDID4, anticorps LYGDI, anticorps Ly-GDI, anticorps RAP1GN1, anticorps RhoGDI2, anticorps Gdid4, anticorps Rho GDP dissociation inhibitor (GDI) gamma, anticorps Rho GDP dissociation inhibitor (GDI) beta S homeolog, anticorps Rho GDP dissociation inhibitor beta, anticorps Rho GDP dissociation inhibitor (GDI) beta, anticorps Rho, GDP dissociation inhibitor (GDI) beta, anticorps arhgdig, anticorps arhgdib.S, anticorps ARHGDIB, anticorps arhgdib, anticorps Arhgdib

Sujet: D4-GDI belongs to the family of Rho GDIs or GDP dissociation inhibitors for the Rho/Rac family of small G proteins, consisting of RhoGDI 1, D4 GDI/RhoGDI2 and Rho GDI3. It inhibits the release of GDP from the Rho proteins, essential for GTP loading and activation of GTPase activity. D4 GDI is located in the cytoplasm and in involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas mediated apoptosis.Synonyms: GDIA2, GDID4, Ly-GDI, RAP1GN1, Rho GDI 2, Rho GDP-dissociation inhibitor 2, Rho-GDI beta, RhoGDI2

Poids moléculaire: 23.0kDa (NP_001166.3)

ID gène: 397

NCBI Accession: NP_001166

UniProt: P52566

Pathways: Caspase Cascade in Apoptosis