Activin A Receptor Type IB/ALK-4 anticorps (C-Term)

N° du produit ABIN499207

Détail du produit anti-Activin A Receptor Type IB/ALK-4 anticorps

Antigène: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Activin A Receptor Type IB/ALK-4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to ACVR1B near the carboxy terminus.

Purification: Affinity chromatography purified via peptide column

Immunogène: ACVR1B antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human ACVR1B.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: ACVR1B antibody can be used for detection of ACVR1B at 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Activin A Receptor Type IB/ALK-4

Antigène: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Autre désignation: Activin Receptor Type 1B (ACVR1B) (ACVR1B Produits)

Synonymes: anticorps ACVR1B, anticorps alk4, anticorps skr2, anticorps alk-4, anticorps xalk4, anticorps actrib, anticorps acvrlk4, anticorps DKFZp469A1614, anticorps 6820432J04, anticorps ActR-IB, anticorps ActRIB, anticorps Acvrlk4, anticorps Alk4, anticorps SKR2, anticorps ACTRIB, anticorps ACVRLK4, anticorps ALK4, anticorps Skr2, anticorps axis, anticorps taram-a, anticorps tarama, anticorps wu:fb75f01, anticorps activin A receptor type 1B, anticorps Activin receptor type-1B, anticorps activin A receptor, type IB, anticorps activin A receptor, type 1B, anticorps activin A receptor type 1Ba, anticorps ACVR1B, anticorps acvr1b, anticorps acv1b, anticorps Acvr1b, anticorps acvr1ba

Sujet: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. ACVR1B, also known as activin receptor-like kinase 4 (ALK4), is a type I receptor for activin and plays major roles in cell differentiation, growth arrest and apoptosis. Like another type I activin receptor ACVR1C, ACVR1B can mediate signaling by ligands such as Nodal, Xnr1, GDF-1/3, activin B and activin AB. In Xenopus embryos, expression of a dominant-negative form of ACVR1B blocked all mesoderm-inducing ligands, while expression of a dominant negative ACVR1C only blocked Nodal and Xnr1 signaling, suggesting that the ACVR1B and ACVR1C possess distinct functions. At least three isoforms of ACVR1B are known to exist. This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1C.Synonyms: ACTR-IB, ACVRLK4, ALK4, Activin receptor type IB, Activin receptor-like kinase 4, SKR2, Serine/threonine-protein kinase receptor R2

ID gène: 91

NCBI Accession: NP_004293

UniProt: P36896