TNFRSF21 anticorps (AA 42-56)

N° du produit ABIN499766

Détail du produit anti-TNFRSF21 anticorps

Antigène: TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))

Épitope: AA 42-56

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF21 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: DR6 antibody was raised against a peptide corresponding to amino acids 42 to 56 of human DR6 precursor.

Purification: DEAE

Immunogène: DR6 antibody was raised against a peptide corresponding to amino acids 42 to 56 of human DR6 precursor.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1/500 to 1/2000. An approximately 68 kDa band can be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur TNFRSF21

Antigène: TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))

Autre désignation: TNFRSF21 / Death Receptor 6 (DR6) (TNFRSF21 Produits)

Synonymes: anticorps TNFRSF21, anticorps tnfrsf21, anticorps MGC146356, anticorps BM-018, anticorps CD358, anticorps DR6, anticorps AA959878, anticorps R74815, anticorps TR7, anticorps dr6, anticorps im:6795346, anticorps wu:fa55e01, anticorps wu:fb02e11, anticorps wu:fc29a09, anticorps wu:fi27h08, anticorps TNF receptor superfamily member 21, anticorps tumor necrosis factor receptor superfamily member 21, anticorps tumor necrosis factor receptor superfamily, member 21, anticorps TNFRSF21, anticorps tnfrsf21, anticorps Tnfrsf21

Sujet: Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor-6 (1). Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappaB and JNK. DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified.Synonyms: Tumor necrosis factor receptor superfamily member 21

ID gène: 27242

UniProt: O75509

Pathways: Regulation of Lipid Metabolism by PPARalpha