EZH1 anticorps (AA 471-510) (Alexa Fluor 680)
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- Antigène Voir toutes EZH1 Anticorps
- EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
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Épitope
- AA 471-510
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EZH1 est conjugé à/à la Alexa Fluor 680
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human EZH1
- Isotype
- IgG
- Top Product
- Discover our top product EZH1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
- Autre désignation
- EZH1 (EZH1 Produits)
- Synonymes
- anticorps KMT6B, anticorps si:ch211-250i3.1, anticorps zgc:136829, anticorps AW557915, anticorps mKIAA0388, anticorps EZH1, anticorps enhancer of zeste 1 polycomb repressive complex 2 subunit, anticorps EZH1, anticorps ezh1, anticorps Ezh1
- Sujet
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Synonyms: Enhancer of zeste homolog 1Drosophila, Enhancer of zeste homolog 1, ENX-2, ENX2, EZH1, EZH1: enhancer of zeste homolog 1 Drosophila, EZH1_HUMAN, Histone-lysine N-methyltransferase EZH1, KIAA0388.
Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Sequence similarities Belongs to the histone-lysine methyltransferase family. EZ subfamily.Contains 1 SET domain.
- ID gène
- 2145
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