GATA5 anticorps (AA 161-260) (Alexa Fluor 680)

N° du produit ABIN5003241

Détail du produit anti-GATA5 anticorps (Alexa Fluor 680)

Antigène: GATA5 (GATA Binding Protein 5 (GATA5))

Épitope: AA 161-260

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATA5 est conjugé à/à la Alexa Fluor 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GATA-5

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GATA5

Antigène: GATA5 (GATA Binding Protein 5 (GATA5))

Autre désignation: GATA5 (GATA5 Produits)

Synonymes: anticorps GATAS, anticorps bB379O24.1, anticorps GATA-5, anticorps GATA5, anticorps xGATA5, anticorps xGATA-5, anticorps xGATA5a, anticorps xGATA5b, anticorps xGATA-5a, anticorps xGATA-5b, anticorps bb379o24.1, anticorps gata-4a, anticorps gata-5a, anticorps gata5, anticorps gata-5b, anticorps cb634, anticorps fau/gata5, anticorps gta5, anticorps GATA binding protein 5, anticorps GATA binding protein 5 S homeolog, anticorps GATA binding protein 5 L homeolog, anticorps GATA5, anticorps Gata5, anticorps gata5, anticorps gata5.S, anticorps gata5.L

Sujet:

Synonyms: GATA binding protein 5, GATA-binding factor 5, GATA5, GATA-5, GATA5_HUMAN, Transcription factor GATA-5.

Background: Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary, lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.

ID gène: 140628