PLEKHM3 anticorps (C-Term)

N° du produit ABIN500513

Détail du produit anti-PLEKHM3 anticorps

Antigène: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLEKHM3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: PLEKHM3 antibody was raised against a 13 amino acid peptide from near the carboxy terminus of human PLEKHM3.

Isotype: IgG

Information d'application

Indications d'application: ELISA: Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur PLEKHM3

Antigène: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Autre désignation: PLEKHM3 (PLEKHM3 Produits)

Synonymes: anticorps PLEKHM1L, anticorps DAPR, anticorps 9430067K14Rik, anticorps A230102O09Rik, anticorps AI449570, anticorps Plekhm1l, anticorps Dapr, anticorps RGD1307151, anticorps pleckstrin homology domain containing, family M, member 3, anticorps pleckstrin homology domain containing M3, anticorps pleckstrin homology domain containing M3 L homeolog, anticorps PLEKHM3, anticorps Plekhm3, anticorps plekhm3.L

Sujet: PLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins. PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2. In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions. Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis.Synonyms: PH domain-containing family M member 3, PLEKHM1L, Pleckstrin homology domain-containing family M member 3

ID gène: 389072

UniProt: Q6ZWE6