POLR3F anticorps (N-Term)

N° du produit ABIN500523

Détail du produit anti-POLR3F anticorps

Antigène: POLR3F (Polymerase (RNA) III (DNA Directed) Polypeptide F, 39 KDa (POLR3F))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR3F est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects POLR3F.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: POLR3F antibody was raised against a 21 amino acid peptide from near the amino terminus of human POLR3F.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur POLR3F

Antigène: POLR3F (Polymerase (RNA) III (DNA Directed) Polypeptide F, 39 KDa (POLR3F))

Autre désignation: POLR3F (POLR3F Produits)

Synonymes: anticorps 2810411G20Rik, anticorps 3010019O03Rik, anticorps 3110032A07Rik, anticorps RPC39, anticorps RPC6, anticorps zgc:56299, anticorps zgc:76983, anticorps RNA polymerase III subunit F, anticorps polymerase (RNA) III (DNA directed) polypeptide F, anticorps POLR3F, anticorps Polr3f, anticorps polr3f

Sujet: The human POLR3F is a component of RNA III polymerase. RNA polymerase III transcribes many essential, small, noncoding RNAs, including the 5S rRNAs and tRNAs. While most pol III-transcribed genes are found scattered throughout the linear chromosome maps or in multiple linear clusters, there is increasing evidence that many of these genes prefer to be spatially clustered, often at or near the nucleolus. This association could create an environment that fosters the coregulation of transcription by pol III with transcription of the large ribosomal RNA repeats by RNA polymerase I (pol I) within the nucleolus. Given the high number of pol III-transcribed genes in all eukaryotic genomes, the spatial organization of these genes is likely to affect a large portion of the other genes in a genome. POLR3F has also been recently identified as an HIV dependency factor (HDF), suggesting that POLR3F may be an important drug target in HIV treatment. At least two isoforms of POLR3F are known to exist.Synonyms: DNA-directed RNA polymerase III subunit F, DNA-directed RNA polymerase III subunit RPC6, RNA polymerase III 39 kDa subunit, RNA polymerase III subunit C6, RPC39, RPC6

ID gène: 10621

UniProt: Q9H1D9